Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10870954 | FEBS Letters | 2013 | 7 Pages |
Abstract
⺠Huge intron 7 spliced from endogenous dystrophin pre-mRNA was analyzed by RT-PCR. ⺠The excised lariat intron 7 had a closed loop but it contained gaps in its sequence. ⺠Two presumed lariats generated from nested introns within intron 7 were detected. ⺠These RNA products were generated concomitantly with dystrophin pre-mRNA splicing. ⺠Proposed model: nested introns are spliced before ultimate splicing in huge intron.
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Authors
Hitoshi Suzuki, Toshiki Kameyama, Kenji Ohe, Toshifumi Tsukahara, Akila Mayeda,