Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10870965 | FEBS Letters | 2013 | 8 Pages |
Abstract
⺠Gli1 specifically occupies Kindlin-2 promoter and inhibits the transcription of Kindlin-2. ⺠Kindlin-2 promotes the expression of Gli1 independent of Hedgehog activator Smoothened. ⺠Kindlin-2 knockdown facilitates the sensitivity of prostate cancer cells to cyclopamine induced prostate cancer cell death.
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Authors
Jianchao Gao, Ammad Aslam Khan, Takashi Shimokawa, Jun Zhan, Staffan Strömblad, Weigang Fang, Hongquan Zhang,