Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10870967 | FEBS Letters | 2013 | 7 Pages |
Abstract
⺠HBx increases the promoter activity and up-regulates the expression of CD46. ⺠HBx up-regulates the expression of CD46 via COX-2/PEG2/STAT3 signaling. ⺠HBx contributes to the resistance of cells to CDC through up-regulating CD46.
Keywords
CREBCD46p-STAT3CD59CD55HBxPGE2COX-2STAT3CDCHCCRNA interferenceRNAisiRNAsmall interference RNAcomplement-dependent cytotoxicityCyclooxygenase-2Immune escapephosphorylated STAT3Signal transducers and activators of transcription 3protectinhepatitis B virus X proteincAMP response element-binding proteinmembrane cofactor proteinProstaglandin E2Hepatocellular carcinoma
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Authors
Shuai Zhang, Changliang Shan, Wenjing Cui, Xiaona You, Yumei Du, Guangyao Kong, Fabao Gao, Lihong Ye, Xiaodong Zhang,