Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10870971 | FEBS Letters | 2013 | 4 Pages |
Abstract
⺠A peptide library was constructed from enzymatic digests of natural bovine brain. ⺠Screening was the recently developed methods, the lag-time of fibril formation. ⺠MALDI-TOF-MS followed by MS/MS of precursor ions revealed peptide sequences. ⺠The peptide accelerates structural conversions of rbPrP originates synaptophysin. ⺠Dose-dependency of the actions was clarified by the synthetic peptide.
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Authors
Kiyoshi Nokihara, Shunsuke Yajima, Akiyoshi Hitara, Tetsuya Sogon, Tadashi Yasuhara,