Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10870975 | FEBS Letters | 2013 | 8 Pages |
Abstract
⺠Six Rho-GEFs are required for serum-induced chemotaxis in MDA-MB-231 cells. ⺠Knockdown of p63RhoGEF suppresses serum-induced RhoA activation and chemotaxis. ⺠Knockdown of p63RhoGEF produces multipolar lamellipodia upon serum stimulation. ⺠p63RhoGEF promotes chemotaxis by limiting lamellipodium formation to one direction.
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Authors
Aya Hayashi, Ryuichi Hiatari, Takuji Tsuji, Kazumasa Ohashi, Kensaku Mizuno,