The heme-copper oxidase superfamily shares a Zn2+-binding motif at the entrance to a proton pathway

Article ID	Journal	Published Year	Pages	File Type
10870986	FEBS Letters	2013	5 Pages	PDF

Abstract

âº Zn2+ inhibits C-type heme-copper oxidases. âº Zn2+ binds to a His near the entrance to the K-pathway analogue for protons. âº The Zn2+ binding motif is the same as in A-type oxidases. âº The Zn2+ motif occurs in evolutionary unrelated proteins.

Keywords

DDM FCCP RCR NOR TMPD cNOR HCuO N,N,N′,N′-tetramethyl-p-phenylenediamine Proton transfer bacterial nitric oxide reductase Liposome respiratory control ratio Nitric oxide reductase Nickel Heme-copper oxidase