| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871004 | FEBS Letters | 2013 | 5 Pages |
Abstract
⺠Interactions between HIV-1 reverse transcriptase and integrase have been modeled. ⺠The model illustrates coordinated regulation of viral DNA production. ⺠High availability of non-integrated DNA depends on the nature of interactions. ⺠The indirect mode of interaction provides a strong negative feedback. ⺠IN·RT and IN·DNA complexes and their formation rates affect RT processivity.
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Authors
Amit Chakraborty, Gui-Quan Sun, Laura Mustavich, Sheng-He Huang, Bai-Lian Li,