| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871006 | FEBS Letters | 2013 | 8 Pages |
Abstract
⺠We found that miR-199a-5p suppresses IR-induced autophagy in MCF-7 cells. ⺠Both DRAM1 and Beclin1 are novel target genes, which are suppressed by miR-199a-5p in MCF-7 cells. ⺠Surprisingly, overexpression of miR-199a-5p promotes autophagy, as well as DRAM1 and Beclin1 expression in MDA-MB-231 cells. ⺠Modulation of miR-199a-5p alters the radiation responsiveness of breast cancer cells.
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Authors
Heqing Yi, Bing Liang, Jie Jia, Nan Liang, Huiying Xu, Guizhi Ju, Shumei Ma, Xiaodong Liu,