| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871079 | FEBS Letters | 2013 | 6 Pages |
Abstract
Treatment of bovine pulmonary smooth muscle cells with U46619 inhibited the Na+/K+ ATPase activity in two parallel pathways: one of which is mediated via glutathionylation of the pump and the other by augmenting the inhibitory activity of the 70Â kDa inhibitor protein of Na+/K+ ATPase. Although phospholemman deglutathionylates the pump leading to its activation, the inhibitor is responsible for irreversible inhibition of Na+/K+ ATPase in an isoform specific manner during treatment of the cells with U46619.
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Authors
Kuntal Dey, Sayed Modinur Rahaman, Tapati Chakraborti, Sajal Chakraborti,