Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871096 | FEBS Letters | 2013 | 7 Pages |
Abstract
⺠Similar binding kinetics of CBAs for monomeric gp120 and trimeric gp140. ⺠Similar binding kinetics of the Ab 2G12 and sCD4 for monomeric gp120 and trimeric gp140. ⺠Two- to threefold stronger affinity of Ab b12 and DC-SIGN for trimeric gp140. ⺠SPR-directed binding kinetics with monomeric gp120 are relevant for native gp140 trimer.
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Authors
Bart Hoorelbeke, Thijs van Montfort, Jie Xue, Patricia J. LiWang, Haruo Tanaka, Yasuhiro Igarashi, Els J.M. Van Damme, Rogier W. Sanders, Jan Balzarini,