Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871144 | FEBS Letters | 2012 | 6 Pages |
Abstract
⺠Urate oxidase is identified as a substrate of SIRT5 protein. ⺠Urate oxidase is located both in mitochondria and peroxisomes. ⺠Urate oxidase is deacetylated and activated in liver mitochondria of SIRT5 Tg mice. ⺠In vitro-synthesized urate oxidase is acetylated when incubated with mitochondria.
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Authors
Yasuhiko Nakamura, Masahito Ogura, Kasane Ogura, Daisuke Tanaka, Nobuya Inagaki,