| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871153 | FEBS Letters | 2012 | 7 Pages |
Abstract
⺠The gum resin of plants boswellia has long been used in Oriental Medicine to prevent amnesia. ⺠β-boswellic acid (BBA) is the major component of the gum. ⺠We investigated the role of BBA in tubulin assembly dynamics by spectrophotometric and electron microscopic methods. ⺠Binding number and constant of BBA with tubulin was elucidated from titration curves. ⺠A binding site and association energy was suggested by the mean of molecular dynamic simulation.
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Authors
Oveis Karima, Gholamhossein Riazi, Sirus Khodadadi, Reza Yousefi, Karim Mahnam, Farzad Mokhtari, Tayebe Cheraghi, Elham Hoveizi, Ali Akbar Moosavi-Movahedi,