| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871156 | FEBS Letters | 2012 | 9 Pages |
Abstract
⺠MCAK/Kif2C levels are reduced during replicative and premature cellular senescence. ⺠MCAK/Kif2C down-regulation induced premature senescence. ⺠MCAK/Kif2C up-regulation in old cells partially reversed cell senescence. ⺠p53 knockdown but not p16 knockdown inhibited cell senescence by MCAK/Kif2C reduction. ⺠MCAK/Kif2C may regulate cellular senescence of human primary cells via a p53 pathway.
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Authors
Mi-Ri Gwon, Jung Hee Cho, Jae-Ryong Kim,