| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871232 | FEBS Letters | 2012 | 7 Pages |
Abstract
⺠Transiently expressed Egr-1 mRNA is identified in HuR mRNP complex. ⺠HuR regulates Egr-1 expression which in turn influences downstream IL-2 activation. ⺠HuR affects polyribosome distribution of Egr-1 mRNA and promotes translation. ⺠HuR controls translation of Egr-1 3â²UTR reporter mRNA. ⺠Our study reveals a role for HuR in regulating early events of T cell activation.
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Authors
Zongchun Mou, Jia You, Qianghai Xiao, Youheng Wei, Juan Yuan, Yong Liu, Gary Brewer, Wei-Jun Ma,