| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871244 | FEBS Letters | 2012 | 9 Pages |
Abstract
⺠KpnK is a novel Ser/Thr kinase produced by multidrug resistant Klebsiella pneumoniae strain. ⺠KpnK regulates K. pneumoniae growth and response to oxidative and gastric stresses. ⺠Deletion of kpnK increases K. pneumoniae susceptibility to β-lactam antibiotics. ⺠The periplasmic and outer membrane stress regulator CpxRKP binds to the kpnK promoter. ⺠Prokaryotic ESTKs may represent novel targets for antibiotic strategies.
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Authors
Vijaya Bharathi Srinivasan, Vasanth Vaidyanathan, Amitabha Mondal, Manjunath Venkataramaiah, Govindan Rajamohan,