Article ID Journal Published Year Pages File Type
10871261 FEBS Letters 2012 6 Pages PDF
Abstract
► Endothelin-1 posttranscriptionally increases HIF1α expression by suppressing proteasome-dependent HIF1α degradation. ► Endothelin-1 stimulates calcineurin activation through endothelin receptor A. ► Calcineurin mediates endothelin-1-induced RACK1 de-phosphorylation. ► RACK1 particularly mediates proteasome-dependent HIF1α degradation.
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Authors
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