| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871273 | FEBS Letters | 2012 | 7 Pages |
Abstract
⺠We performed systematic mutational analysis of Mdm2 acidic domain. ⺠Two separate regions involved in p53 degradation were identified. ⺠Only one of the regions is required for p53 ubiquitylation. ⺠The other plays a role in a post-ubiquitylation step required for p53 degradation.
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Authors
Pavlina Dolezelova, Katerina Cetkovska, Karen H. Vousden, Stjepan Uldrijan,