| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871277 | FEBS Letters | 2012 | 9 Pages |
Abstract
⺠LRFN4 signaling induces elongation of THP-1 via actin cytoskeleton reorganization. ⺠ LRFN4 complexes with 14-3-3 and NCK proteins to induce LRFN4-mediated elongation. ⺠ An SH3-2 domain of NCK1 interacts with the proline-rich region of LRFN4. ⺠ A 14-3-3 dimer interacts with both phospho-Ser 585 LRFN4 and phospho-Ser 85 NCK1. ⺠ A Rho family small GTPase, Rac1, is involved in LRFN4-mediated elongation.
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Authors
Shu Konakahara, Yuki Suzuki, Takao Kawakami, Maki Saitou, Masunori Kajikawa, Yasuhiko Masuho, Junya Kohroki,