Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871284 | FEBS Letters | 2012 | 6 Pages |
Abstract
⺠Treatment of keratinocytes or skin tumor cells with recombinant dermokine-β inhibited phosphorylation of ERK1/2. ⺠Exposure of keratinocytes to dermokine-β stimulated its gene expression. ⺠Carboxyl-terminus domain of dermokine-β confers its functions. ⺠Dermokine-β physically interacted with GRP78. ⺠Down-regulation of GRP78 expression abrogated the functions of dermokine-β.
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Authors
Kiyoshi Higashi, Minoru Hasegawa, Chikako Yokoyama, Taro Tachibana, Shinichi Mitsui, Koichi Saito,