Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871292 | FEBS Letters | 2012 | 5 Pages |
Abstract
⺠GM3 synthase (GM3S) activity of CHO-K1 cells increases when transfected with GD3 synthase (GD3S). ⺠The products of the GM3S assay were GM3 in CHO-K1 cells but GM3, GD3 and GT3in GD3S transfected cells. ⺠GM3 formed in the complex GalT1/GM3S/GD3S remains bound and is converted into GD3 and GT3 by GD3S. ⺠GM3Sfreeof GM3 is ready for new turns of LacCer sialylation, resulting in its apparent activation.
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Authors
Waldo Spessott, Pilar M. Crespo, José Luis Daniotti, Hugo J.F. Maccioni,