Article ID Journal Published Year Pages File Type
10871299 FEBS Letters 2012 8 Pages PDF
Abstract
► miR-376a was found frequently down-regulated in HCC cell lines and tissues. ► Over-expression of miR-376a in Huh7 cells inhibited proliferation and induced apoptosis. ► p85α (PIK3R1) was identified as a direct and functional target of miR-376a in Huh7 cells. ► Down-regulation of miR-376a may contribute to the development of HCC by targeting p85α.
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