Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871299 | FEBS Letters | 2012 | 8 Pages |
Abstract
⺠miR-376a was found frequently down-regulated in HCC cell lines and tissues. ⺠Over-expression of miR-376a in Huh7 cells inhibited proliferation and induced apoptosis. ⺠p85α (PIK3R1) was identified as a direct and functional target of miR-376a in Huh7 cells. ⺠Down-regulation of miR-376a may contribute to the development of HCC by targeting p85α.
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Authors
Yongxia Zheng, Lei Yin, Huan Chen, Shengsheng Yang, Chuanyong Pan, Shan Lu, Mingyong Miao, Binghua Jiao,