| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871300 | FEBS Letters | 2012 | 7 Pages |
Abstract
⺠Clostridium botulinum neurotoxin forms a progenitor complex with hemagglutinins. ⺠X-ray structures of the hemagglutinin/oligosaccharides complexes were determined. ⺠α2-3-Sialylated oligosaccharide bound to hemagglutinin tightly. ⺠α2-6-Sialylated oligosaccharide bound to hemagglutinin with a low occupancy. ⺠A binding assay also showed a higher affinity for α2-3-sialylated oligosaccharide.
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Authors
Satoshi Yamashita, Hiromi Yoshida, Noboru Uchiyama, Yukari Nakakita, Shin-ichi Nakakita, Takashi Tonozuka, Keiji Oguma, Atsushi Nishikawa, Shigehiro Kamitori,