| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871306 | FEBS Letters | 2012 | 8 Pages |
Abstract
⺠AKT and GSK-3β are modified by O-GlcNAcylation. ⺠GlcNAcylation regulates AKT and GSK-3β differently in kidney HEK-293FT cells. ⺠GlcNAcylation does not affect AKT and GSK-3β in hepatic HepG2 cells. ⺠GlcNAcylation regulates phosphorylation of AKT negatively in neuronal cells. ⺠Regulation of AKT and GSK-3β by O-GlcNAc is protein- and cell type-specific.
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Authors
Jianhua Shi, Shiliang Wu, Chun-ling Dai, Yi Li, Inge Grundke-Iqbal, Khalid Iqbal, Fei Liu, Cheng-Xin Gong,