Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871308 | FEBS Letters | 2012 | 9 Pages |
Abstract
⺠BCG infection induce miR-21 de novo expression both in vitro and in vivo. ⺠miR-21 impairs BCG induced Th1 responses. ⺠miR-21 reduced IL-12 production from APC and promoted APC apoptosis. ⺠Il12p35 and Bcl2 to be the direct target of miR-21.
Keywords
Related Topics
Life Sciences
Agricultural and Biological Sciences
Plant Science
Authors
Zhongwen Wu, Haifeng Lu, Jifang Sheng, Lanjuan Li,