Article ID Journal Published Year Pages File Type
10871323 FEBS Letters 2012 8 Pages PDF
Abstract
► Ghrelin inhibits glucose-dependent insulinotropic action of GLP-1 in rat islets. ► Ghrelin inhibits GLP-1-induced increases in cAMP and [Ca2+]i in islet β-cells. ► Ghrelin antagonist enhances cAMP production and GLP-1-induced insulin release. ► Exogenous and endogenous ghrelin modulates ability of GLP-1 and related medicines.
Related Topics
Life Sciences Agricultural and Biological Sciences Plant Science
Authors
, , , , , , ,