| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871328 | FEBS Letters | 2013 | 8 Pages |
Abstract
Non-coding RNAs (ncRNAs) are increasingly recognized as central players in diverse biological processes. Upon DNA damage, the DNA damage response (DDR) elicits a complex signaling cascade, which includes the induction of multiple ncRNA species. Recent studies indicate that DNA-damage induced ncRNAs contribute to regulation of cell cycle, apoptosis and DNA repair, and thus play a key role in maintaining genome stability. This review summarizes the emerging role of ncRNAs in DNA damage and repair.
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Authors
Vivek Sharma, Tom Misteli,