| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871364 | FEBS Letters | 2012 | 7 Pages |
Abstract
⺠We have identified a transcriptional repressor of HIV-1 replication. ⺠Overexpression of ZBRK1 represses transcriptional activity of the HIV-1 LTR. ⺠The depletion of ZBRK1 leads to activation of the HIV-1 LTR. ⺠TRIM28 binding is required for ZBRK1 repressor activity. ⺠These results indicate that ZBRK1 could be involved in antiretroviral defense.
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Authors
Hironori Nishitsuji, Makoto Abe, Reila Sawada, Hiroshi Takaku,