Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871371 | FEBS Letters | 2012 | 5 Pages |
Abstract
⺠MiR-136 is downregulated in human glioma cell lines and tissues. ⺠Ectopic expression of miR-136 is able to sensitize glioma cells to cisplatin-induced apoptosis. ⺠AEG-1 and BCL-2 are two directly targets of miR-136. ⺠Expression of ectopic AEG-1 or Bcl-2 partially abrogates the effect of miR-136.
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Authors
Yi Yang, Jueheng Wu, Hongyu Guan, Junchao Cai, Lishan Fang, Jun Li, Mengfeng Li,