| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871377 | FEBS Letters | 2012 | 8 Pages |
Abstract
⺠We tried reprogramming terminally differentiated B cells into erythroid lineage. ⺠We introduced various transcription factors into activated B cells by retrovirus. ⺠Erythroid conversion of B cells was achieved by introducing GATA-1, SCL and C/EBPα. ⺠Converted cells retained rearrangement of IgH gene, confirming their B cell origin. ⺠Converted cells presented erythroid morphology and expressed erythrocyte genes.
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Authors
Ken Sadahira, Yumi Fukuchi, Hiroyoshi Kunimono, Masatoshi Sakurai, Yasuo Ikeda, Shinichiro Okamoto, Hideaki Nakajima,