| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871386 | FEBS Letters | 2012 | 6 Pages |
Abstract
⺠Scaffold recognizing imipenem in a Vibrio alkaline phosphatase (AP). ⺠Scaffold detected by an in silico analysis. ⺠Other APs (from E. coli and shrimp) were not inhibited by the tested β-lactams. ⺠None of the APs had any detectable β-lactamase activity. ⺠Gain of metallo-β-lactamase activity in APs could result in antibiotic resistance.
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Authors
Sandeep Chakraborty, Bjarni Ásgeirsson, Renu Minda, Lipika Salaye, Jean-Marie Frère, Basuthkar J. Rao,