Article ID Journal Published Year Pages File Type
10871390 FEBS Letters 2012 9 Pages PDF
Abstract
► ICV Ang II induced significant tau phosphorylation independent on blood pressure. ► High-dose Ang II infusion impaired cognitive performance. ► Ang II induced tau phosphorylation by stimulating AT1R and activating GSK3β. ► Inhibition of GSK3β attenuated tau phosphorylation and cognitive impairment.
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Preview
Central angiotensin II-induced Alzheimer-like tau phosphorylation in normal rat brains
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