Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871391 | FEBS Letters | 2012 | 7 Pages |
Abstract
⺠We find PROX1 directly binds to TWIST1 promoter to repress its transcription. ⺠PROX1 inhibits TWIST1-induced AKT2 to reduce cell migration and invasion. ⺠We provide a molecular basis by which PROX1 functions as a tumor suppressor.
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Authors
Tsung-Ming Chang, Wen-Chun Hung,