Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871418 | FEBS Letters | 2012 | 6 Pages |
Abstract
⺠Rev1 is involved in bypass replication of damaged DNA-translesion synthesis (TLS). ⺠Rev1 provides a binding platform for other major TLS DNA polymerases. ⺠Rev1 interacts with TLS polymerases via its C-terminal domain (Rev1-CT). ⺠NMR reveals independent binding sites of Rev1-CT for Polη and Rev7 subunit of Polζ. ⺠Rev1-CT is a scaffold that can accommodate multiple TLS polymerases at the same time.
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Authors
Yulia Pustovalova, Irina Bezsonova, Dmitry M. Korzhnev,