Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871419 | FEBS Letters | 2012 | 7 Pages |
Abstract
⺠TRIAD1 is required for p53 activation and stabilization. ⺠TRIAD1 antagonizes MDM2-mediated p53 degradation. ⺠TRIAD1 inhibits the interaction between p53 and MDM2. ⺠TRIAD1 interacts with the C-terminus of p53. ⺠TRIAD1 negatively regulates MDM2 function by p53-mediated cell growth suppression.
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Authors
Seunghee Bae, Jin Hyuk Jung, Karam Kim, In-Sook An, Soo-Yeon Kim, Jae Ho Lee, In-Chul Park, Young-Woo Jin, Su-Jae Lee, Sungkwan An,