Article ID Journal Published Year Pages File Type
10871419 FEBS Letters 2012 7 Pages PDF
Abstract
► TRIAD1 is required for p53 activation and stabilization. ► TRIAD1 antagonizes MDM2-mediated p53 degradation. ► TRIAD1 inhibits the interaction between p53 and MDM2. ► TRIAD1 interacts with the C-terminus of p53. ► TRIAD1 negatively regulates MDM2 function by p53-mediated cell growth suppression.
Related Topics
Life Sciences Agricultural and Biological Sciences Plant Science
Authors
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