Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871466 | FEBS Letters | 2012 | 6 Pages |
Abstract
⺠The SH3 domain of STAM2 binds ubiquitin and constitutes the third ubiquitin binding domain of STAM2. ⺠UBPY competes with ubiquitin for binding to the SH3 domain of STAM2. ⺠The binding of UBPY and ubiquitin to the SH3 domain does not require the UIM domain of the STAM2 protein. ⺠The SH3 domain of STAM2 could be involved in cargo concentration at the ESCRT-0 level.
Keywords
UIMmonoubiquitinubiquitin interacting motifVHSUbDUbiquitin binding domainassociated molecule with the SH3 domain of STAMDUBSH3ESCRTMVBHRSnuclear magnetic resonanceSrc homology 3 domainEndocytosisdeubiquitinating enzymeAMshmultivesicular bodyProtein–protein interactionstamendosomal sorting complexes required for transport
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Authors
Anja Lange, Mouhamad-Baligh Ismail, Gwladys Rivière, Maggy Hologne, Denis Lacabanne, Florence Guillière, Jean-Marc Lancelin, Isabelle Krimm, Olivier Walker,