Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871478 | FEBS Letters | 2012 | 6 Pages |
Abstract
⺠Substrate binding to GcpE involves a large domain rearrangement. ⺠Its structure at 1.55 Ã
resolution can be exploited for inhibitor design. ⺠The apical Fe of the [4Fe-4S] cluster is ligated to the C3 oxygen of MEcPP. ⺠Active site analysis provides valuable mechanistic information.
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Authors
Ingo Rekittke, Hassan Jomaa, Ulrich Ermler,