| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871518 | FEBS Letters | 2011 | 4 Pages |
Abstract
⺠Regucalin (RGN) or senescence marker protein 30 is involved in Ca2+ homeostasis. ⺠RGN expression alters agonist and thapsigargin induced Ca2+ mobilization in cells. ⺠RGN also increases the expression of SERCA Ca2+ pumps by increasing transcription. ⺠Decrease in RGN may contribute to age-dependent dys-regulation of Ca2+ homeostasis.
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![Regucalcin (RGN/SMP30) alters agonist- and thapsigargin-induced cytosolic [Ca2+] transients in cells by increasing SERCA Ca2+ATPase levels](/preview/png/10871518.png "First Page Preview: Regucalcin (RGN/SMP30) alters agonist- and thapsigargin-induced cytosolic [Ca2+] transients in cells by increasing SERCA Ca2+ATPase levels")
Authors
Pei Lai, Nga Chi Yip, Francesco Michelangeli,