Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871520 | FEBS Letters | 2011 | 7 Pages |
Abstract
⺠NAADP as a new intracellular second messenger in astrocytes. ⺠NAADP receptors are present in lysosome-related vesicles. ⺠NAADP-AM increases intracellular calcium concentration. ⺠The lysosomal disruptor compound glycyl-l-phenylalanine 2-naphthylamide inhibits NAADP-AM responses. ⺠NAADP mediates ATP and ET-1 but not bradykinin-induced calcium mobilization from lysosome-related stores.
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Authors
Miquel Barceló-Torns, Alexander M. Lewis, Albert Gubern, David Barneda, Duncan Bloor-Young, Fernado Picatoste, Grant C. Churchill, Enrique Claro, Roser Masgrau,