Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871542 | FEBS Letters | 2012 | 5 Pages |
Abstract
⺠We identify homologies between the toxin domains of CDI systems and PF04740 proteins. ⺠Several PF04740 C-terminal domains have cytotoxic RNase activities. ⺠The activity of each PF04740 protein is specifically blocked by cognate antitoxin. ⺠We conclude that PF04740 proteins constitute a new toxin-antitoxin family.
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Authors
Laura E. Holberger, Fernando Garza-Sánchez, James Lamoureux, David A. Low, Christopher S. Hayes,