Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871544 | FEBS Letters | 2012 | 6 Pages |
Abstract
⺠Sensitivity of yeast frataxin-deficient cells to hydrogen peroxide is partially mediated by metacaspase. ⺠In the absence of metacaspase, frataxin-deficient cells recover antioxidant capacity and heme biosynthesis. ⺠Metacaspase is implicated in mitochondrial energy metabolism and intracellular redox control.
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Authors
Sophie Lefevre, Dominika Sliwa, Françoise Auchère, Caroline Brossas, Christoph Ruckenstuhl, Nicole Boggetto, Emmanuel Lesuisse, Frank Madeo, Jean-Michel Camadro, Renata Santos,