Article ID Journal Published Year Pages File Type
10871553 FEBS Letters 2012 5 Pages PDF
Abstract
► Electron microscopic analyses prove the elimination of insulin receptors from caveolae in the state of insulin resistance. ► This was accompanied by a concomitant increase of ganglioside GM3 in adipocytes. ► Blocking of the GM3 increase restores the number of insulin receptors in caveolae.
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Life Sciences Agricultural and Biological Sciences Plant Science
Preview
Dissociation of the insulin receptor from caveolae during TNFα-induced insulin resistance and its recovery by d-PDMP
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