Article ID Journal Published Year Pages File Type
10871561 FEBS Letters 2012 9 Pages PDF
Abstract
► 14-3-3 Interacts with LKB1 via recognizing phosphorylated Thr336 residue. ► 14-3-3 Inhibits LKB1 phosphorylation of its substrates. ► 14-3-3 Interferes with the interaction between LKB1 and its substrates. ► 14-3-3 Attenuates LKB1-mediated G1 cell cycle arrest and apoptosis. ► This regulation by 14-3-3 may provide a negative feedback control for LKB1 function.
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