Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871564 | FEBS Letters | 2012 | 6 Pages |
Abstract
⺠SHP drastically stabilizes Mdm2 protein by abrogating Mdm2 self-ubiquitination. ⺠Mdm2 causes SHP degradation under p53-deficient conditions. ⺠SHP K170 residue is critical for SHP and Mdm2 interaction and cross-regulation.
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Authors
Zhihong Yang, Li Wang,