Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871572 | FEBS Letters | 2012 | 5 Pages |
Abstract
⺠Catechols were identified as inhibitors of the histone-lysine demethylase KDM4C. ⺠The inhibitors were selective towards KDM4C and KDM6A and had no effect on PHF8. ⺠One inhibitor restored H3K9me3 levels in KDM4C transfected U2-OS cells.
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Authors
Anders L. Nielsen, Line H. Kristensen, Karen B. Stephansen, Jan B.L. Kristensen, Charlotte Helgstrand, Michael Lees, Paul Cloos, Kristian Helin, Michael Gajhede, Lars Olsen,