| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871609 | FEBS Letters | 2012 | 9 Pages |
Abstract
⺠Gastric cancer (GC) is a major concern worldwide. ⺠E-cadherin plays a major role in cell-cell adhesion. ⺠Germline mutations in CDH1 predispose to hereditary diffuse gastric cancer. ⺠E-cadherin alterations are pivotal for tumour initiation and progression. ⺠Main E-cadherin deregulation mechanisms:(epi)genetic/post-translational/trafficking.
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Authors
PatrÃcia Carneiro, Maria Sofia Fernandes, Joana Figueiredo, Joana Caldeira, Joana Carvalho, Hugo Pinheiro, Marina Leite, Soraia Melo, PatrÃcia Oliveira, Joana Simões-Correia, Maria José Oliveira, Fátima Carneiro, Céu Figueiredo, Joana Paredes,