Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871695 | FEBS Letters | 2011 | 6 Pages |
Abstract
⺠The fungus Cryptococcus neoformans is an important pathogen of AIDS patients. ⺠The transcription factor Cir1 regulates iron uptake and virulence in C. neoformans. ⺠We examined the influence of iron levels on the abundance of Cir1. ⺠Iron deprivation results in reduced abundance of Cir1. ⺠Cir1 stability is also regulated by redox conditions and proteasome activity.
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Authors
Won Hee Jung, James W. Kronstad,