Article ID Journal Published Year Pages File Type
10871714 FEBS Letters 2012 5 Pages PDF
Abstract
► Artificial ribonucleases (aRNases) do inactivate the enveloped DNA-containing vaccinia virus. ► Amphyphilic aRNases posses chaotropic, membranolytic and ribonuclease activities. ► Vaccinia virus inactivation was caused by altering the structure of viral surface proteins and membrane disruption. ► Amphyphilic aRNases are novel universal agents inactivating both RNA- and DNA-containing viruses.
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