Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871714 | FEBS Letters | 2012 | 5 Pages |
Abstract
⺠Artificial ribonucleases (aRNases) do inactivate the enveloped DNA-containing vaccinia virus. ⺠Amphyphilic aRNases posses chaotropic, membranolytic and ribonuclease activities. ⺠Vaccinia virus inactivation was caused by altering the structure of viral surface proteins and membrane disruption. ⺠Amphyphilic aRNases are novel universal agents inactivating both RNA- and DNA-containing viruses.
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Authors
A.A. Fedorova, E.P. Goncharova, E.I. Ryabchikova, V.V. Vlasov, M.A. Zenkova,