| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871728 | FEBS Letters | 2011 | 8 Pages |
Abstract
⺠The Fanconi anemia (FA) is a bone marrow and cancer predisposition syndrome. ⺠The FA pathway is responsible for repair of interstrand DNA crosslinks. ⺠FA core complex ubiquitylates FANCI and FANCD2 which localize to chromatin and direct repair. ⺠Ubiquitin interaction motifs are used to recruit nucleases to sites of damage. ⺠Deubiquitylation plays an important role in terminating DNA damage signaling.
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Authors
Elizabeth Garner, Agata Smogorzewska,