| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871730 | FEBS Letters | 2011 | 8 Pages |
Abstract
⺠Genome is constantly exposed to various endogenous and exogenous agents that cause DNA double strand breaks (DSBs). ⺠DSBs, if left unrepaired, cause genome instability and cancer. ⺠The ubiquitin-proteasome system is virtually involved in any cellular process. ⺠By summarizing the current literature we observed that the UPS is an integral part of DSB repair. ⺠Based on this, we propose new perspectives for anti-cancer therapy.
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Authors
Kristijan Ramadan, Mayura Meerang,