Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871742 | FEBS Letters | 2011 | 9 Pages |
Abstract
⺠We constructed a cDNA library of Saos2 cells to identify NELL-1 interacting proteins. ⺠APR3 was identified as a direct binding protein of NELL-1 through phage display. ⺠The inhibitory effect of APR3 on osteoblast proliferation is enhanced by NELL-1. ⺠NELL-1 and APR3 binding can promote osteoblast differentiation and mineralization.
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Authors
Xuan Zou, Jia Shen, Feng Chen, Kang Ting, Zhong Zheng, Shen Pang, Janette N. Zara, John S. Adams, Chia Soo, Xinli Zhang,